Tuesday, September 7th, 2010

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Title:
Cardiac Metastasis from Poorly Differentiated Carcinoma of the Cervix: A Case Report
Authors:  Emily S. Miller, M.D., Anna V. Hoekstra, M.D., Jean A. Hurteau, M.D., and  Gustavo C. Rodriguez, M.D.
 
BACKGROUND: Disease metastatic to the heart from cervical carcinoma is rare and associated with a poor prognosis. Multimodality treatment has been shown to provide palliative benefit.
CASE: A woman presented with stage Ib2 cervical cancer metastatic to the tricuspid valve. She presented with small bowel obstruction from a small bowel metastasis 4 years after initial treatment with chemoradiation. Computed tomographic imaging revealed a small bowel mass as well as a pericardial effusion. Cardiac magnetic resonance imaging showed a tricuspid mass. Endomyocardial biopsy confirmed metastatic disease consistent with a cervical primary. The patient was treated with bowel resection, systemic chemotherapy and cardiac radiation. She died of cardiac failure 8 months after diagnosis of the cardiac lesion.
CONCLUSION: Cervical cancer metastatic to the heart is rare and associated with a poor prognosis. Selected patients may benefit from multimodality treatment. (J Reprod Med 2010;55:78–80)
Keywords:  cardiac neoplasms, metastasis, uterine cervical cancer, X-radiation
   
   
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